Farscape

A really cool, serial sci-fi show about an American astronaut sent through a wormhole to the other side of the universe with freaky aliens. While at first it was an ensemble show, it devolved into a show solely focused between the main character, John Crichton, and his love interest, Aeryn Sun. The ratings concurrently declined with this change of focus, predominantly in the fourth season, leading to its cancellation by The Sci-Fi Network.