StarTropics

StarTropics is an NES game released in 1990. The game has a 15-year-old pitcher named Mike Jones visting his scientist uncle, Dr. Steve Jones, AKA Dr. J, on C-Island. When Mike gets there, however, he finds his uncle missing and is sent by Chief Coralcola on a quest to find him. Fighting his way through monster-filled tunnels on numerous islands, Mike soon learns that his uncle was kidnapped by aliens. In the end, Mike confornts and defeats their leader, Zoda, destroys their spaceship and, in addition to his uncle, saves a friendly alien race, the Argonians, from extinction.

It was inspired by the movie Predator.